Recycling to discover something new: the role of autophagy in kidney disease.

Journal Article (Journal Article)

This year, the Nobel Prize in Physiology or Medicine was awarded to Yoshinori Ohsumi for his groundbreaking work in dissecting the mechanisms of autophagy, a cellular process resulting in the organized degradation of cytoplasmic components. Ohsumi's work paved the way for subsequent studies that demonstrated critical roles for autophagy in modulating both acute and chronic kidney injury. This work may lead to future therapeutic approaches that target the autophagy system to prevent or treat kidney diseases.

Full Text

Duke Authors

Cited Authors

  • Leventhal, JS; Wyatt, CM; Ross, MJ

Published Date

  • January 2017

Published In

Volume / Issue

  • 91 / 1

Start / End Page

  • 4 - 6

PubMed ID

  • 28003091

Electronic International Standard Serial Number (EISSN)

  • 1523-1755

Digital Object Identifier (DOI)

  • 10.1016/j.kint.2016.11.004


  • eng

Conference Location

  • United States