Higher hemoglobin levels and quality of life in patients with advanced chronic kidney disease: no longer a moving target?

Journal Article (Journal Article)

International clinical practice guidelines for the management of anemia in chronic kidney disease suggest target hemoglobin levels ≤ 11.5 g/dl (115 g/l), with individualized consideration of slightly higher hemoglobin targets to improve quality of life. An updated meta-analysis of randomized trials demonstrates no significant improvement in quality of life with erythropoietin-stimulating agent therapy targeting higher hemoglobin levels. Limitations of the available data suggest that individualized targets should nonetheless remain an option in future clinical practice guidelines.

Full Text

Duke Authors

Cited Authors

  • Wyatt, CM; Drueke, TB

Published Date

  • May 2016

Published In

Volume / Issue

  • 89 / 5

Start / End Page

  • 971 - 973

PubMed ID

  • 27083270

Electronic International Standard Serial Number (EISSN)

  • 1523-1755

Digital Object Identifier (DOI)

  • 10.1016/j.kint.2016.03.001


  • eng

Conference Location

  • United States