Will a new tenofovir prodrug for the treatment of HIV reduce the risk of nephrotoxicity?
Journal Article (Journal Article)
The widely used antiretroviral agent tenofovir disoproxil fumarate has been associated with proximal tubular injury and decreased glomerular filtration rate in HIV-infected individuals. Phase 3 trials of a new prodrug, tenofovir alafenamide, suggest a lower potential for kidney injury.
Full Text
Duke Authors
Cited Authors
- Wyatt, CM
Published Date
- January 2016
Published In
Volume / Issue
- 89 / 1
Start / End Page
- 5 - 6
PubMed ID
- 26759035
Electronic International Standard Serial Number (EISSN)
- 1523-1755
Digital Object Identifier (DOI)
- 10.1016/j.kint.2015.11.014
Language
- eng
Conference Location
- United States