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Living donor liver transplantation.

Publication ,  Journal Article
Goldaracena, N; Barbas, AS
Published in: Curr Opin Organ Transplant
April 2019

PURPOSE OF REVIEW: As experience grows, living donor liver transplantation (LDLT) has become an effective treatment option to overcome the deceased donor organ shortage. RECENT FINDINGS: Donor safety is the highest priority in LDLT. Strict donor selection according to structured protocols and center experience are the main factors that determine donor safety. However, with increased experience, many centers have explored increasing organ availability within living donation by means of ABO incompatible LDLT, dual graft LDLT, and anonymous living donation. Also, this growing experience in LDLT has allowed the transplant community to cautiously explore the role of liver transplantation for hepatocellular carcinoma outside of Milan criteria and patients with unresectable colorectal liver metastases. SUMMARY: LDLT has become established as a viable strategy to ameliorate the organ shortage experienced by centers around the world. Improved understanding of this technique has allowed the improved utilization of live donor graft resources, without compromising donor safety. Moreover, LDLT may offer some advantages over deceased donor liver transplantation and a unique opportunity to assess the broader applicability of liver transplantation.

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Published In

Curr Opin Organ Transplant

DOI

EISSN

1531-7013

Publication Date

April 2019

Volume

24

Issue

2

Start / End Page

131 / 137

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Surgery
  • Living Donors
  • Liver Transplantation
  • Liver Neoplasms
  • Humans
  • Donor Selection
  • Carcinoma, Hepatocellular
  • 3204 Immunology
  • 3202 Clinical sciences
 

Citation

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Goldaracena, N., & Barbas, A. S. (2019). Living donor liver transplantation. Curr Opin Organ Transplant, 24(2), 131–137. https://doi.org/10.1097/MOT.0000000000000610
Goldaracena, Nicolas, and Andrew S. Barbas. “Living donor liver transplantation.Curr Opin Organ Transplant 24, no. 2 (April 2019): 131–37. https://doi.org/10.1097/MOT.0000000000000610.
Goldaracena N, Barbas AS. Living donor liver transplantation. Curr Opin Organ Transplant. 2019 Apr;24(2):131–7.
Goldaracena, Nicolas, and Andrew S. Barbas. “Living donor liver transplantation.Curr Opin Organ Transplant, vol. 24, no. 2, Apr. 2019, pp. 131–37. Pubmed, doi:10.1097/MOT.0000000000000610.
Goldaracena N, Barbas AS. Living donor liver transplantation. Curr Opin Organ Transplant. 2019 Apr;24(2):131–137.

Published In

Curr Opin Organ Transplant

DOI

EISSN

1531-7013

Publication Date

April 2019

Volume

24

Issue

2

Start / End Page

131 / 137

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Surgery
  • Living Donors
  • Liver Transplantation
  • Liver Neoplasms
  • Humans
  • Donor Selection
  • Carcinoma, Hepatocellular
  • 3204 Immunology
  • 3202 Clinical sciences