Metabolic Teamwork in the Stem Cell Niche.


Journal Article

Nearby cells can support stem cell differentiation, but the metabolic activities in stem cell niches are unknown. A recent study (Rodríguez-Colman et al., 2017) reveals a metabolic partnership in the intestinal stem cell niche: glycolysis in niche Paneth cells provides lactate to drive mitochondrial oxidative phosphorylation in intestinal stem cells.

Full Text

Duke Authors

Cited Authors

  • Roper, J; Yilmaz, ÖH

Published Date

  • May 2, 2017

Published In

Volume / Issue

  • 25 / 5

Start / End Page

  • 993 - 994

PubMed ID

  • 28467944

Pubmed Central ID

  • 28467944

Electronic International Standard Serial Number (EISSN)

  • 1932-7420

Digital Object Identifier (DOI)

  • 10.1016/j.cmet.2017.04.019


  • eng

Conference Location

  • United States