Neoadjuvant therapy followed by prostatectomy for clinically localized prostate cancer.
Journal Article (Journal Article;Review)
The results of this assessment of the literature indicated that neoadjuvant therapy followed by prostatectomy may improve long-term outcomes for patients with high-risk localized disease. In addition, this approach provides a paradigm for evaluating the activity and mechanism of action of new agents as correlative studies are facilitated by the availability of tumor tissue before and after therapy. The authors determined that a multidisciplinary approach involving oncologists, urologists, and pathologists is critical to the success of this model. Recent and ongoing studies of neoadjuvant therapy followed by prostatectomy were reviewed.
Full Text
Duke Authors
Cited Authors
- Sonpavde, G; Chi, KN; Powles, T; Sweeney, CJ; Hahn, N; Hutson, TE; Galsky, MD; Berry, WR; Kadmon, D
Published Date
- December 15, 2007
Published In
Volume / Issue
- 110 / 12
Start / End Page
- 2628 - 2639
PubMed ID
- 17941029
International Standard Serial Number (ISSN)
- 0008-543X
Digital Object Identifier (DOI)
- 10.1002/cncr.23085
Language
- eng
Conference Location
- United States