Age-related infertility.

Journal Article (Journal Article;Review)

Oocyte number and quality decrease with advancing age. Thus, fecundity decreases as age increases, with a more rapid decline after the mid-30s. Patients more than 35 years old should receive prompt evaluation for causes of infertility after no more than 6 months of attempted conception. Patients with abnormal tests of ovarian reserve have a poorer prognosis and may need more expedited and aggressive treatment. Although oocyte donation is the best method to overcome age-related infertility, other treatment options may help women proceed quicker toward pregnancy. Patients at an advanced age should be counseled and evaluated before undergoing infertility treatments.

Full Text

Duke Authors

Cited Authors

  • Crawford, NM; Steiner, AZ

Published Date

  • March 2015

Published In

Volume / Issue

  • 42 / 1

Start / End Page

  • 15 - 25

PubMed ID

  • 25681837

Electronic International Standard Serial Number (EISSN)

  • 1558-0474

Digital Object Identifier (DOI)

  • 10.1016/j.ogc.2014.09.005


  • eng

Conference Location

  • United States