Mobile health as a viable strategy to enhance stroke risk factor control: A systematic review and meta-analysis.

Journal Article (Journal Article;Review;Systematic Review)

BACKGROUND: With the rapid growth worldwide in cell-phone use, Internet connectivity, and digital health technology, mobile health (mHealth) technology may offer a promising approach to bridge evidence-treatment gaps in stroke prevention. We aimed to evaluate the effectiveness of mHealth for stroke risk factor control through a systematic review and meta-analysis. METHODS: We searched PubMed from January 1, 2000 to May 17, 2016 using the following keywords: mobile health, mHealth, short message, cellular phone, mobile phone, stroke prevention and control, diabetes mellitus, hypertension, hyperlipidemia and smoking cessation. We performed a meta-analysis of all eligible randomized control clinical trials that assessed a sustained (at least 6months) effect of mHealth. RESULTS: Of 78 articles identified, 13 met eligibility criteria (6 for glycemic control and 7 for smoking cessation) and were included for the final meta-analysis. There were no eligible studies for dyslipidemia or hypertension. mHealth resulted in greater Hemoglobin A1c reduction at 6months (6 studies; 663 subjects; SMD: -0.44; 95% CI: [-0.82, -0.06], P=0.02; Mean difference of decrease in HbA1c: -0.39%; 95% CI: [-0.74, -0.04], P=0.03). mHealth also lead to relatively higher smoking abstinence rates at 6months (7 studies; 9514 subjects; OR: 1.54; 95% CI: [1.24, 1.90], P<0.0001). CONCLUSIONS: Our meta-analysis supports that use of mHealth improves glycemic control and smoking abstinence rates.

Full Text

Duke Authors

Cited Authors

  • Liu, S; Feng, W; Chhatbar, PY; Liu, Y; Ji, X; Ovbiagele, B

Published Date

  • July 15, 2017

Published In

Volume / Issue

  • 378 /

Start / End Page

  • 140 - 145

PubMed ID

  • 28566151

Pubmed Central ID

  • PMC5503473

Electronic International Standard Serial Number (EISSN)

  • 1878-5883

Digital Object Identifier (DOI)

  • 10.1016/j.jns.2017.04.050


  • eng

Conference Location

  • Netherlands