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A Protocol for Sedation Free MRI and PET Imaging in Adults with Autism Spectrum Disorder.

Publication ,  Journal Article
Smith, CJ; Bhanot, A; Norman, E; Mullett, JE; Bilbo, SD; McDougle, CJ; Zürcher, NR; Hooker, JM
Published in: Journal of autism and developmental disorders
July 2019

Imaging technologies such as positron emission tomography (PET) and magnetic resonance imaging (MRI) present unparalleled opportunities to investigate the neural basis of autism spectrum disorder (ASD). However, challenges such as deficits in social interaction, anxiety around new experiences, impaired language abilities, and hypersensitivity to sensory stimuli make participating in neuroimaging studies challenging for individuals with ASD. In this commentary, we describe the existent training protocols for preparing individuals with ASD for PET/MRI scans and our own experience developing a training protocol to facilitate the inclusion of low-functioning adults with ASD in PET-MRI studies. We hope to raise awareness of the need for more information exchange between research groups about lessons learned in this context in order to include the entire disease spectrum in neuroimaging studies.

Duke Scholars

Published In

Journal of autism and developmental disorders

DOI

EISSN

1573-3432

ISSN

0162-3257

Publication Date

July 2019

Volume

49

Issue

7

Start / End Page

3036 / 3044

Related Subject Headings

  • Positron-Emission Tomography
  • Neuroimaging
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Developmental & Child Psychology
  • Autism Spectrum Disorder
  • Adult
  • 52 Psychology
  • 42 Health sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Smith, C. J., Bhanot, A., Norman, E., Mullett, J. E., Bilbo, S. D., McDougle, C. J., … Hooker, J. M. (2019). A Protocol for Sedation Free MRI and PET Imaging in Adults with Autism Spectrum Disorder. Journal of Autism and Developmental Disorders, 49(7), 3036–3044. https://doi.org/10.1007/s10803-019-04010-3
Smith, C. J., A. Bhanot, E. Norman, J. E. Mullett, S. D. Bilbo, C. J. McDougle, N. R. Zürcher, and J. M. Hooker. “A Protocol for Sedation Free MRI and PET Imaging in Adults with Autism Spectrum Disorder.Journal of Autism and Developmental Disorders 49, no. 7 (July 2019): 3036–44. https://doi.org/10.1007/s10803-019-04010-3.
Smith CJ, Bhanot A, Norman E, Mullett JE, Bilbo SD, McDougle CJ, et al. A Protocol for Sedation Free MRI and PET Imaging in Adults with Autism Spectrum Disorder. Journal of autism and developmental disorders. 2019 Jul;49(7):3036–44.
Smith, C. J., et al. “A Protocol for Sedation Free MRI and PET Imaging in Adults with Autism Spectrum Disorder.Journal of Autism and Developmental Disorders, vol. 49, no. 7, July 2019, pp. 3036–44. Epmc, doi:10.1007/s10803-019-04010-3.
Smith CJ, Bhanot A, Norman E, Mullett JE, Bilbo SD, McDougle CJ, Zürcher NR, Hooker JM. A Protocol for Sedation Free MRI and PET Imaging in Adults with Autism Spectrum Disorder. Journal of autism and developmental disorders. 2019 Jul;49(7):3036–3044.
Journal cover image

Published In

Journal of autism and developmental disorders

DOI

EISSN

1573-3432

ISSN

0162-3257

Publication Date

July 2019

Volume

49

Issue

7

Start / End Page

3036 / 3044

Related Subject Headings

  • Positron-Emission Tomography
  • Neuroimaging
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Developmental & Child Psychology
  • Autism Spectrum Disorder
  • Adult
  • 52 Psychology
  • 42 Health sciences