Enhanced depth penetration by dual-axis optical coherence tomography

Published

Conference Paper

© 2019 SPIE. Optical imaging techniques generally offer shallow penetration depths due to high scattering in biological tissue. We have recently developed dual-axis optical coherence tomography (DA-OCT) for interferometric imaging at extended depths. By illuminating and collecting at oblique angles, multiply forward scattered photons from deeper penetration depths were favorably detected. A Monte Carlo study demonstrated a >12-fold increase in signal-to-background ratio (SBR) in skin tissue at 1 mm depth by DA-OCT. A 1300 nm DA-OCT system was designed and constructed, offering an imaging depth of up to 2 mm in skin tissue.

Full Text

Duke Authors

Cited Authors

  • Zhao, Y; Chu, KK; Wax, A

Published Date

  • January 1, 2019

Published In

Volume / Issue

  • 10867 /

International Standard Serial Number (ISSN)

  • 1605-7422

International Standard Book Number 13 (ISBN-13)

  • 9781510623767

Digital Object Identifier (DOI)

  • 10.1117/12.2507242

Citation Source

  • Scopus