FGF23 or PTH: which comes first in CKD ?
Journal Article (Journal Article)
In the past 40 years, disordered mineral metabolism has been among the most intensely studied areas of nephrology. A June 2010 PubMed search for 'secondary hyperparathyroidism and kidney disease' yielded 5866 references. Among these are papers documenting the development and application of numerous therapeutic agents-including calcitriol, vitamin D analogs, phosphate binders, and cinacalcet-that remain in widespread use in the day-to-day management of dialysis patients worldwide. However, almost 6000 papers later, fundamental pathophysiological concepts remain unclear, particularly regarding the early pathogenesis of disordered mineral metabolism.
- Isakova, T; Wolf, MS
- November 2010
Volume / Issue
- 78 / 10
Start / End Page
- 947 - 949
Electronic International Standard Serial Number (EISSN)
Digital Object Identifier (DOI)
- United States