Cohort Profile: Perinatal depression and child socioemotional development ; the Bachpan cohort study from rural Pakistan.

Journal Article (Journal Article)

PURPOSE: This is a prospective pregnancy-birth cohort designed to investigate the effects of depression on socioemotional development of children. Perinatal depression is a risk factor for poor child development and for many it has a recurring chronic course. Thus, the exposure to depression can continue through the early years of the child with detrimental developmental outcomes. PARTICIPANTS: Between October 2014 and February 2016, we recruited 1154 pregnant women from a rural subdistrict of Pakistan. Data include longitudinal and repeated measures of maternal psychosocial measures and child growth, cognitive and socioemotional measures. Follow-up include mother-child dyad assessments at 3rd, 6th, 12th, 24th and 36th months of child age. All these follow-ups are community based at the household level. We have competed baseline assessment. FINDINGS TO DATE: Of the eligible dyads, we followed 885 (76.6%), 929 (91%) and 940 (93.3%) at 3, 6 and 12 months post-childbirth. We include a subsample mother-child dyad DNA and inflammatory biomarkers, 73 and 104, respectively. FUTURE PLANS: While we continue to do 24-month and 36-month follow-up assessments, we plan to follow these mother-child dyads up to the age of 7-8 years with some children being exposed to at least 1 year of school environment. Investigators interested in learning more about the study can contact ( and (

Full Text

Duke Authors

Cited Authors

  • Sikander, S; Ahmad, I; Bates, LM; Gallis, J; Hagaman, A; O'Donnell, K; Turner, EL; Zaidi, A; Rahman, A; Maselko, J

Published Date

  • May 5, 2019

Published In

Volume / Issue

  • 9 / 5

Start / End Page

  • e025644 -

PubMed ID

  • 31061029

Pubmed Central ID

  • PMC6502044

Electronic International Standard Serial Number (EISSN)

  • 2044-6055

Digital Object Identifier (DOI)

  • 10.1136/bmjopen-2018-025644


  • eng

Conference Location

  • England