Combination Therapy for Alzheimer's Disease: Perspectives of the EU/US CTAD Task Force.

Journal Article (Journal Article)

Combination therapy is expected to play an important role for the treatment of Alzheimer's disease (AD). In October 2018, the European Union-North American Clinical Trials in Alzheimer's Disease Task Force (EU/US CTAD Task Force) met to discuss scientific, regulatory, and logistical challenges to the development of combination therapy for AD and current efforts to address these challenges. Task Force members unanimously agreed that successful treatment of AD will likely require combination therapy approaches that target multiple mechanisms and pathways. They further agreed on the need for global collaboration and sharing of data and resources to accelerate development of such approaches.

Full Text

Duke Authors

Cited Authors

  • Gauthier, S; Alam, J; Fillit, H; Iwatsubo, T; Liu-Seifert, H; Sabbagh, M; Salloway, S; Sampaio, C; Sims, JR; Sperling, B; Sperling, R; Welsh-Bohmer, KA; Touchon, J; Vellas, B; Aisen, P

Published Date

  • 2019

Published In

Volume / Issue

  • 6 / 3

Start / End Page

  • 164 - 168

PubMed ID

  • 31062826

Electronic International Standard Serial Number (EISSN)

  • 2426-0266

Digital Object Identifier (DOI)

  • 10.14283/jpad.2019.12


  • eng

Conference Location

  • Switzerland