Skip to main content

Physiologic Effects of Noninvasive Ventilation.

Publication ,  Journal Article
MacIntyre, NR
Published in: Respir Care
June 2019

Noninvasive ventilation (NIV) has a number of physiologic effects similar to invasive ventilation. The major effects are to augment minute ventilation and reduce muscle loading. These effects, in turn, can have profound effects on the patient's ventilator control system, both acutely and chronically. Because NIV can be supplied with PEEP, the maintenance of alveolar recruitment is also made possible and the triggering load imposed by auto-PEEP can be reduced. NIV (or simply mask CPAP) can maintain upper-airway patency during sleep in patients with obstructive sleep apnea. NIV can have multiple effects on cardiac function. By reducing venous return, it can help in patients with heart failure or fluid overload, but it can compromise cardiac output in others. NIV can also increase right ventricular afterload or function to reduce left ventricular afterload. Potential detrimental physiologic effects of NIV are ventilator-induced lung injury, auto-PEEP development, and discomfort/muscle overload from poor patient-ventilator interactions.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Respir Care

DOI

EISSN

1943-3654

Publication Date

June 2019

Volume

64

Issue

6

Start / End Page

617 / 628

Location

United States

Related Subject Headings

  • Ventilator-Induced Lung Injury
  • Respiratory System
  • Respiratory Physiological Phenomena
  • Respiratory Muscles
  • Respiratory Insufficiency
  • Positive-Pressure Respiration
  • Noninvasive Ventilation
  • Monitoring, Physiologic
  • Humans
  • 3202 Clinical sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
MacIntyre, N. R. (2019). Physiologic Effects of Noninvasive Ventilation. Respir Care, 64(6), 617–628. https://doi.org/10.4187/respcare.06635
MacIntyre, Neil R. “Physiologic Effects of Noninvasive Ventilation.Respir Care 64, no. 6 (June 2019): 617–28. https://doi.org/10.4187/respcare.06635.
MacIntyre NR. Physiologic Effects of Noninvasive Ventilation. Respir Care. 2019 Jun;64(6):617–28.
MacIntyre, Neil R. “Physiologic Effects of Noninvasive Ventilation.Respir Care, vol. 64, no. 6, June 2019, pp. 617–28. Pubmed, doi:10.4187/respcare.06635.
MacIntyre NR. Physiologic Effects of Noninvasive Ventilation. Respir Care. 2019 Jun;64(6):617–628.

Published In

Respir Care

DOI

EISSN

1943-3654

Publication Date

June 2019

Volume

64

Issue

6

Start / End Page

617 / 628

Location

United States

Related Subject Headings

  • Ventilator-Induced Lung Injury
  • Respiratory System
  • Respiratory Physiological Phenomena
  • Respiratory Muscles
  • Respiratory Insufficiency
  • Positive-Pressure Respiration
  • Noninvasive Ventilation
  • Monitoring, Physiologic
  • Humans
  • 3202 Clinical sciences