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Minimum visible retinal lesions from pico-and femtosecond laser pulses

Publication ,  Conference
Roach, WP; Toth, CA; Stein, CD; Noojin, GD; Stolarski, DJ; Cain, CP
Published in: Proceedings of SPIE - The International Society for Optical Engineering
August 17, 1994

Threshold measurements for Minimum Visible Lesions (MVL) at the retina are reported for femtosecond (fs) and picosecond (ps) laser pulses in Rhesus monkey' eyes using visible wavelengths. The 50% probability for damage (ED50) dosages are calculated for 1 hour and 24 hour post-exposures at the 95% confidence level. The ED50 values are found to decrease with pulsewidth down to 600 fs. At 90 fs the ED50 dosages were noted to increase slightly when compared with the 3 ps and 600 fs values. Fluorescein angiography (FA) was accomplished at both 1 hour and 24 hour post-exposure and did not demonstrate lower threshold for damage, which has been the case for MVL's created with longer pulse durations (nanoseconds). At the 90 fs pulse duration, MVL's were not observed below 0.1 ii). At energies greater than 0.1 jiJ, both MVL and the absence of MVL's were observed up to 1.4 pJ. Above 1.4 11J all energies delivered showed MVL development. Out of 138 data points taken at 90 fs, 94 were between 0.1 and 1.4 p.J, and the observed lesions are distributed with approximately 50% probability throughout this energy range.

Duke Scholars

Published In

Proceedings of SPIE - The International Society for Optical Engineering

DOI

EISSN

1996-756X

ISSN

0277-786X

Publication Date

August 17, 1994

Volume

2134

Start / End Page

10 / 21

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 4009 Electronics, sensors and digital hardware
  • 4006 Communications engineering
 

Citation

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Roach, W. P., Toth, C. A., Stein, C. D., Noojin, G. D., Stolarski, D. J., & Cain, C. P. (1994). Minimum visible retinal lesions from pico-and femtosecond laser pulses. In Proceedings of SPIE - The International Society for Optical Engineering (Vol. 2134, pp. 10–21). https://doi.org/10.1117/12.182931
Roach, W. P., C. A. Toth, C. D. Stein, G. D. Noojin, D. J. Stolarski, and C. P. Cain. “Minimum visible retinal lesions from pico-and femtosecond laser pulses.” In Proceedings of SPIE - The International Society for Optical Engineering, 2134:10–21, 1994. https://doi.org/10.1117/12.182931.
Roach WP, Toth CA, Stein CD, Noojin GD, Stolarski DJ, Cain CP. Minimum visible retinal lesions from pico-and femtosecond laser pulses. In: Proceedings of SPIE - The International Society for Optical Engineering. 1994. p. 10–21.
Roach, W. P., et al. “Minimum visible retinal lesions from pico-and femtosecond laser pulses.” Proceedings of SPIE - The International Society for Optical Engineering, vol. 2134, 1994, pp. 10–21. Scopus, doi:10.1117/12.182931.
Roach WP, Toth CA, Stein CD, Noojin GD, Stolarski DJ, Cain CP. Minimum visible retinal lesions from pico-and femtosecond laser pulses. Proceedings of SPIE - The International Society for Optical Engineering. 1994. p. 10–21.

Published In

Proceedings of SPIE - The International Society for Optical Engineering

DOI

EISSN

1996-756X

ISSN

0277-786X

Publication Date

August 17, 1994

Volume

2134

Start / End Page

10 / 21

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 4009 Electronics, sensors and digital hardware
  • 4006 Communications engineering