Retinal hemorrhagic lesions from femtosecond visible laser pulses

We present our clinical evaluation of hemorrhagic and non-hemorrhagic 90 fs single pulses in rabbits and ri1 The rabbit and primate eye present unique in vivo models for evaluation Of retinal and choroidal laser induced hemorrhages with distinct differences in their retinal anatomy. We found two different hemorrhagic events to occur in the posterior pole with delivery of 90 fs pulses. First, in the Dutch Belted rabbit, we found large amounts of energy per pulse (from 20 to 60 times ED5O) were required for formation of subretinal hemorrhages. Second, in the Rhesus monkey, we found significant numbers of small intraretinal hemorrhages from relatively low energy 90 fs pulses. Both the Dutch Belted rabbit and the Rhesus monkey failed to consistently show subretinal hemorrhagic lesions from very high pulse energies.

Duke Scholars

Author Cynthia Ann Toth Ophthalmology, Vitreoretinal Diseases & Surgery