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Paradoxical associations between familial affective responsiveness, stress, and amygdala reactivity.

Publication ,  Journal Article
Farber, MJ; Romer, AL; Kim, MJ; Knodt, AR; Elsayed, NM; Williamson, DE; Hariri, AR
Published in: Emotion (Washington, D.C.)
June 2019

Studies of early life extremes such as trauma, abuse, and neglect highlight the critical importance of quality caregiving in the development of brain circuits supporting emotional behavior and mental health. The impact of normative variability in caregiving on such biobehavioral processes, however, is poorly understood. Here, we provide initial evidence that even subtle variability in normative caregiving maps onto individual differences in threat-related brain function and, potentially, associated psychopathology in adolescence. Specifically, we report that greater familial affective responsiveness is associated with heightened amygdala reactivity to interpersonal threat, particularly in adolescents having experienced relatively low recent stress. These findings extend the literature on the effects of caregiving extremes on brain function to subtle, normative variability but suggest that presumably protective factors may be associated with increased risk-related amygdala reactivity. We consider these paradoxical associations with regard to studies of basic associative threat learning and further consider their relevance for understanding potential effects of caregiving on psychological development. (PsycINFO Database Record (c) 2019 APA, all rights reserved).

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Published In

Emotion (Washington, D.C.)

DOI

EISSN

1931-1516

ISSN

1528-3542

Publication Date

June 2019

Volume

19

Issue

4

Start / End Page

645 / 654

Related Subject Headings

  • Stress, Psychological
  • Male
  • Humans
  • Female
  • Experimental Psychology
  • Emotions
  • Amygdala
  • Adolescent
  • 52 Psychology
  • 1702 Cognitive Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Farber, M. J., Romer, A. L., Kim, M. J., Knodt, A. R., Elsayed, N. M., Williamson, D. E., & Hariri, A. R. (2019). Paradoxical associations between familial affective responsiveness, stress, and amygdala reactivity. Emotion (Washington, D.C.), 19(4), 645–654. https://doi.org/10.1037/emo0000467
Farber, Madeline J., Adrienne L. Romer, M Justin Kim, Annchen R. Knodt, Nourhan M. Elsayed, Douglas E. Williamson, and Ahmad R. Hariri. “Paradoxical associations between familial affective responsiveness, stress, and amygdala reactivity.Emotion (Washington, D.C.) 19, no. 4 (June 2019): 645–54. https://doi.org/10.1037/emo0000467.
Farber MJ, Romer AL, Kim MJ, Knodt AR, Elsayed NM, Williamson DE, et al. Paradoxical associations between familial affective responsiveness, stress, and amygdala reactivity. Emotion (Washington, DC). 2019 Jun;19(4):645–54.
Farber, Madeline J., et al. “Paradoxical associations between familial affective responsiveness, stress, and amygdala reactivity.Emotion (Washington, D.C.), vol. 19, no. 4, June 2019, pp. 645–54. Epmc, doi:10.1037/emo0000467.
Farber MJ, Romer AL, Kim MJ, Knodt AR, Elsayed NM, Williamson DE, Hariri AR. Paradoxical associations between familial affective responsiveness, stress, and amygdala reactivity. Emotion (Washington, DC). 2019 Jun;19(4):645–654.

Published In

Emotion (Washington, D.C.)

DOI

EISSN

1931-1516

ISSN

1528-3542

Publication Date

June 2019

Volume

19

Issue

4

Start / End Page

645 / 654

Related Subject Headings

  • Stress, Psychological
  • Male
  • Humans
  • Female
  • Experimental Psychology
  • Emotions
  • Amygdala
  • Adolescent
  • 52 Psychology
  • 1702 Cognitive Sciences