Physostigmine in the Treatment of y-Hydroxybutyric Acid Overdose


Journal Article

The widespread abuse of the recreational drug γ-hydroxybutyric acid has resulted in several reports of overdose leading to coma. The use of a short-acting anticholinesterase agent such as physostigmine as a potential reversal agent has been proposed previously. We report 2 cases of γ-hydroxybutyric acid-induced coma that rapidly reversed with intravenous administration of physostigmine. © 2000 Mayo Foundation for Medical Education and Research.

Full Text

Duke Authors

Cited Authors

  • Yates, SW; Viera, AJ

Published Date

  • January 1, 2000

Published In

Volume / Issue

  • 75 / 4

Start / End Page

  • 401 - 402

International Standard Serial Number (ISSN)

  • 0025-6196

Digital Object Identifier (DOI)

  • 10.4065/75.4.401

Citation Source

  • Scopus