What risk of death would people take to be cured of HIV and why? A survey of people living with HIV.

Published online

Journal Article

People living with HIV (PLWHIV) can reasonably expect near-normal longevity, yet many express a willingness to assume significant risks to be cured. We surveyed 200 PLWHIV who were stable on antiretroviral therapy (ART) to quantify associations between the benefits they anticipate from a cure and their risk tolerance for curative treatments. Sixty-five per cent expected their health to improve if cured of HIV, 41% predicted the virus would stop responding to medications over the next 20 years and 54% predicted experiencing serious medication side effects in the next 20 years. Respondents' willingness to risk death for a cure varied widely (median 10%, 75th percentile 50%). In multivariate analyses, willingness to risk death was associated with expected long-term side effects of ART, greater financial resources and being employed (all P < 0.05) but was not associated with perceptions of how their health would improve if cured.

Full Text

Duke Authors

Cited Authors

  • Murray, BR; Kratka, A; Scherr, KA; Eyal, N; Blumenthal-Barby, J; Freedberg, KA; Kuritzkes, DR; Hammitt, JK; Edifor, R; Katz, MN; Pollak, KI; Zikmund-Fisher, BJ; Halpern, SD; Barks, MC; Ubel, PA

Published Date

  • April 1, 2019

Published In

Volume / Issue

  • 5 / 2

Start / End Page

  • 109 - 115

PubMed ID

  • 31191914

Pubmed Central ID

  • 31191914

International Standard Serial Number (ISSN)

  • 2055-6640


  • eng

Conference Location

  • England