Effect of interstitial anisotropy and the extracellular volume conductor on action potential morphology in a thin layer of cardiac tissue

Conference Paper

We simulated conduction in a thin layer of cardiac tissue using both a bidomain and monodomain model of the structure. The two models predict similar wavefronts and action potential shapes when the intracellular and interstitial spaced are both insulated. The most significant differences in active tissue are observed in the foot of the transmembrane potential, the portion of the upstroke due to passive current flow. The two models yield markedly different behavior when the interstitial space is not insulated but permitted to exchange currents with a thin layer of bounding fluid.

Full Text

Duke Authors

Cited Authors

  • Henriquez, CS; Hooke, NF

Published Date

  • January 1, 1992

Published In

Volume / Issue

  • 2 /

Start / End Page

  • 600 - 601

International Standard Serial Number (ISSN)

  • 1557-170X

International Standard Book Number 10 (ISBN-10)

  • 0780307852

Digital Object Identifier (DOI)

  • 10.1109/IEMBS.1992.5761130

Citation Source

  • Scopus