Differential diagnoses of vague neurologic symptoms in patients without significant medical history provide challenges for the advanced practice registered nurse to accurately diagnose a condition. A detailed inquiry highlights the nurse practitioner's ability to hear the patient's story, formulate an evidence-based diagnosis, and collaborate with the patient for delivering safe and effective care with appropriate referrals for specialist follow-up care. This case study emphasizes the importance of clustering symptoms that align, allowing for a better understanding of vague complaints, which helps the provider in clinical decision making.