Prevalence of obstructive sleep apnea in suicidal patients with major depressive disorder.

Journal Article (Journal Article)

In this paper, we report the rate of previously undiagnosed obstructive sleep apnea (OSA) in a randomized clinical trial (RCT) of suicidal patients with major depressive disorder (MDD). One hundred and twenty-five suicidal adults with MDD were recruited into a RCT. None were suspected to have OSA. Fourteen percent met diagnostic criteria for OSA. The Apnea Hypopnea Index (AHI) was predicted by increasing age, male sex, and higher Body Mass Index. However, neither the degree of daytime sleepiness nor the degree of insomnia predicted AHI severity. A high degree of suspicion is warranted for OSA in suicidal patients with MDD, and for patients with treatment-resistant depression. identifier: NCT01689909.

Full Text

Duke Authors

Cited Authors

  • McCall, WV; Benca, RM; Rumble, ME; Case, D; Rosenquist, PB; Krystal, AD

Published Date

  • September 2019

Published In

Volume / Issue

  • 116 /

Start / End Page

  • 147 - 150

PubMed ID

  • 31238203

Pubmed Central ID

  • PMC6606377

Electronic International Standard Serial Number (EISSN)

  • 1879-1379

Digital Object Identifier (DOI)

  • 10.1016/j.jpsychires.2019.06.015


  • eng

Conference Location

  • England