Synthesis and texture manipulation of screening mammograms using conditional generative adversarial network

Conference Paper

Annotated data availability has always been a major limiting f actor for the development of algorithms in the field of computer aided diagnosis. The purpose of this study is to investigate the feasibility of using a conditional generative adversarial network (GAN) to synthesize high resolution mammography images with semantic control. We feed a binary mammographic texture map to the generator to synthesize a full-field digital-mammogram (FFDM). Our results show the generator quickly learned to grow anatomical details around the edges within the texture mask. However, we found the training unstable and the quality of generated images unsatisfactory due to the inherent limitation of latent space and sample space mapping by the pix2pix framework. In order to synthesize high resolution mammography images with semantic control, we identified the critical challenge is to build the efficient mappings of binary textures with a great variety of pattern realizations with the image domain.

Full Text

Duke Authors

Cited Authors

  • Kong, D; Ren, Y; Hou, R; Grimm, LJ; Marks, JR; Lo, JY

Published Date

  • January 1, 2019

Published In

Volume / Issue

  • 10950 /

International Standard Serial Number (ISSN)

  • 1605-7422

International Standard Book Number 13 (ISBN-13)

  • 9781510625471

Digital Object Identifier (DOI)

  • 10.1117/12.2513125

Citation Source

  • Scopus