Inadequate oral feeding as a barrier to discharge in moderately preterm infants.

Journal Article (Journal Article)

OBJECTIVES: The objectives describe the frequency that inadequate oral feeding (IOF) is the reason why moderately preterm (MPT) infants remain hospitalized and its association with neonatal morbidities. STUDY DESIGN: Prospective study using the NICHD Neonatal Research Network MPT Registry. Multivariable logistic regression was used to describe associations between IOF and continued hospitalization at 36 weeks postmenstrual age (PMA). RESULT: A total of 6017 MPT infants from 18 centers were included. Three-thousand three-seventy-six (56%) remained hospitalized at 36 weeks PMA, of whom 1262 (37%) remained hospitalized due to IOF. IOF was associated with RDS (OR 2.02, 1.66-2.46), PDA (OR 1.86, 1.37-2.52), sepsis (OR 2.36, 95% 1.48-3.78), NEC (OR 16.14, 7.27-35.90), and BPD (OR 3.65, 2.56-5.21) compared to infants discharged and was associated with medical NEC (OR 2.06, 1.19-3.56) and BPD (OR 0.46, 0.34-0.61) compared to infants remaining hospitalized for an alternative reason. CONCLUSION: IOF is the most common barrier to discharge in MPT infants, especially among those with neonatal morbidities.

Full Text

Duke Authors

Cited Authors

  • Edwards, L; Cotten, CM; Smith, PB; Goldberg, R; Saha, S; Das, A; Laptook, AR; Stoll, BJ; Bell, EF; Carlo, WA; D'Angio, CT; DeMauro, SB; Sanchez, PJ; Shankaran, S; Van Meurs, KP; Vohr, BR; Walsh, MC; Malcolm, WF; Eunice Kennedy Shriver National Institute of Child Health and Human Development,

Published Date

  • September 2019

Published In

Volume / Issue

  • 39 / 9

Start / End Page

  • 1219 - 1228

PubMed ID

  • 31296918

Pubmed Central ID

  • PMC7246972

Electronic International Standard Serial Number (EISSN)

  • 1476-5543

Digital Object Identifier (DOI)

  • 10.1038/s41372-019-0422-x


  • eng

Conference Location

  • United States