Beyond cost-effectiveness: A five-step framework for appraising the value of health technologies in Asia-Pacific.

Journal Article (Journal Article)

Given resource constraints and the potential for increasingly high-cost, cost-effective medicines to become available, policymakers require strategies that go beyond cost-effectiveness when making resource allocation decisions. This manuscript presents a five-step framework that complements traditional health technology assessment (HTA) guidance documents that policymakers in Asia-Pacific and elsewhere may consider when setting up HTA guidelines and/or evaluating whether or not to subsidize a medicine or other health innovations. The framework recommends that subsidy decisions be based on five criteria: the relative burden of the condition as compared with other conditions (step 1), comparative and cost-effectiveness of the medicine (steps 2 and 3), the short-term impact on the budget (step 4), and other considerations including patient and societal preferences (step 5). Our approach, which is a complement to traditional HTA guidance documents, is not prescriptive but provides an evidence-based framework that HTA agencies in Asia-Pacific can follow as they aim to deliver value-based medicines to their constituents.

Full Text

Duke Authors

Cited Authors

  • Finkelstein, EA; Krishnan, A; Doble, B

Published Date

  • January 2020

Published In

Volume / Issue

  • 35 / 1

Start / End Page

  • 397 - 408

PubMed ID

  • 31290187

Electronic International Standard Serial Number (EISSN)

  • 1099-1751

International Standard Serial Number (ISSN)

  • 0749-6753

Digital Object Identifier (DOI)

  • 10.1002/hpm.2851


  • eng