Correlation of spectral-domain optical coherence tomography with fundus fluorescein angiography in an infant with retinal hamartomas.


Journal Article

To describe the correlation between the surface morphology on spectral-domain optical coherence tomography (SD-OCT) and leakage pattern on fundus fluorescein angiography (FFA) in an infant with multiple retinal hamartomas.An Asian Indian female infant was found to have 2 retinal lesions in the right eye and 1 in the left eye during Retcam (Clarity MSI, CA, USA) screening for retinopathy of prematurity at 45 weeks postmenstrual age. Spectral-domain optical coherence tomography on the hand-held OCT (Envisu 2300, Bioptigen, NC, USA) and FFA on the Retcam 3 were performed under monitoring in the office.Spectral-domain OCT detected all 3 lesions but only 1 lesion was detected on FFA. While this lesion had an irregular surface with overlying vitreoretinal (VR) traction on SD-OCT, the other 2 lesions not detected on FFA were smooth and had no VR traction. After a follow-up to 18 months corrected age, there was no change in the morphology of any of the lesions.It is possible to characterize retinal hamartomas in infants using SD-OCT and correlate them with FFA. Spectral-domain OCT examination can be used to diagnose and monitor lesions even if they are not detectable on angiography.

Full Text

Cited Authors

  • Chidambara, L; Jayadev, C; Mangalesh, S; Sivakumar, M; Shetty, B; Vinekar, A

Published Date

  • October 21, 2015

Published In

Volume / Issue

  • 25 / 6

Start / End Page

  • e106 - e108

PubMed ID

  • 26109023

Pubmed Central ID

  • 26109023

Electronic International Standard Serial Number (EISSN)

  • 1724-6016

International Standard Serial Number (ISSN)

  • 1120-6721

Digital Object Identifier (DOI)

  • 10.5301/ejo.5000640


  • eng