Selective hyperpolarization of heteronuclear singlet states via pulsed microtesla SABRE.

Published

Journal Article

Signal Amplification By Reversible Exchange (SABRE) and its heteronuclear variant SABRE in SHield Enables Alignment Transfer to Heteronuclei create large nuclear magnetization in target ligands, exploiting level crossings in an iridium catalyst that transiently binds both the ligands and parahydrogen. This requires a specific, small magnetic field to match Zeeman splittings to scalar couplings. Here, we explore a different strategy, direct creation of heteronuclear singlet states in the target ligands, which produces enhanced signals at other field strengths, including zero field. We also show that pulsed methods (including pulsed field nulling) coherently and selectively pump such singlets, affording a significant enhancement on the resulting hyperpolarization.

Full Text

Duke Authors

Cited Authors

  • Tanner, CPN; Lindale, JR; Eriksson, SL; Zhou, Z; Colell, JFP; Theis, T; Warren, WS

Published Date

  • July 2019

Published In

Volume / Issue

  • 151 / 4

Start / End Page

  • 044201 -

PubMed ID

  • 31370556

Pubmed Central ID

  • 31370556

Electronic International Standard Serial Number (EISSN)

  • 1089-7690

International Standard Serial Number (ISSN)

  • 0021-9606

Digital Object Identifier (DOI)

  • 10.1063/1.5108644

Language

  • eng