Perspectives on Scedosporium species and Lomentospora prolificans in lung transplantation: Results of an international practice survey from ESCMID fungal infection study group and study group for infections in compromised hosts, and European Confederation of Medical Mycology.

Published

Journal Article

BACKGROUND: Scedosporium species and Lomentospora prolificans (S/L) are the second most common causes of invasive mold infections following Aspergillus in lung transplant recipients. METHODS: We assessed the current practices on management of S/L colonization/infection of the lower respiratory tract before and after lung transplantation in a large number of lung transplant centers through an international practice survey from October 2016 to March 2017. RESULTS: A total of 51 respondents from 45 lung transplant centers (17 countries, 4 continents) answered the survey (response rate 58%). S/L colonization was estimated to be detected in candidates by 48% of centers. Only 18% of the centers used a specific medium to detect S/L colonization. Scedosporium spp. colonization was a contraindication to transplantation in 10% of centers whereas L prolificans was a contraindication in 31%; 22% of centers declared having had 1-5 recipients infected with S/L in the past 5 years. CONCLUSIONS: This survey gives an overview of the current practices regarding S/L colonization and infection in lung transplant centers worldwide and underscores the need of S/L culture procedure standardization before implementing prospective studies.

Full Text

Duke Authors

Cited Authors

  • Rammaert, B; Puyade, M; Cornely, OA; Seidel, D; Grossi, P; Husain, S; Picard, C; Lass-Flörl, C; Manuel, O; Le Pavec, J; Lortholary, O; SCEDO-LUNG collaborative group,

Published Date

  • October 2019

Published In

Volume / Issue

  • 21 / 5

Start / End Page

  • e13141 -

PubMed ID

  • 31283872

Pubmed Central ID

  • 31283872

Electronic International Standard Serial Number (EISSN)

  • 1399-3062

Digital Object Identifier (DOI)

  • 10.1111/tid.13141

Language

  • eng

Conference Location

  • Denmark