Skip to main content
Journal cover image

Characterization of blue light irradiation effects on pathogenic and nonpathogenic Escherichia coli.

Publication ,  Journal Article
Abana, CM; Brannon, JR; Ebbott, RA; Dunigan, TL; Guckes, KR; Fuseini, H; Powers, J; Rogers, BR; Hadjifrangiskou, M
Published in: Microbiologyopen
August 2017

Blue light irradiation (BLI) is an FDA-approved method for treating certain types of infections, like acne, and is becoming increasingly attractive as an antimicrobial strategy as the prevalence of antibiotic-resistant "superbugs" rises. However, no study has delineated the effectiveness of BLI throughout different bacterial growth phases, especially in more BLI-tolerant organisms such as Escherichia coli. While the vast majority of E. coli strains are nonpathogenic, several E. coli pathotypes exist that cause infection within and outside the gastrointestinal tract. Here, we compared the response of E. coli strains from five phylogenetic groups to BLI with a 455 nm wavelength (BLI455 ), using colony-forming unit and ATP measurement assays. Our results revealed that BLI455 is not bactericidal, but can retard E. coli growth in a manner that is dependent on culture age and strain background. This observation is critical, given that bacteria on and within mammalian hosts are found in different phases of growth.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Microbiologyopen

DOI

EISSN

2045-8827

Publication Date

August 2017

Volume

6

Issue

4

Location

England

Related Subject Headings

  • Microbial Viability
  • Light
  • Escherichia coli
  • Colony Count, Microbial
  • Adenosine Triphosphate
  • 3107 Microbiology
  • 3101 Biochemistry and cell biology
  • 0605 Microbiology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Abana, C. M., Brannon, J. R., Ebbott, R. A., Dunigan, T. L., Guckes, K. R., Fuseini, H., … Hadjifrangiskou, M. (2017). Characterization of blue light irradiation effects on pathogenic and nonpathogenic Escherichia coli. Microbiologyopen, 6(4). https://doi.org/10.1002/mbo3.466
Abana, Courtney M., John R. Brannon, Rebecca A. Ebbott, Taryn L. Dunigan, Kirsten R. Guckes, Hubaida Fuseini, Jennifer Powers, Bridget R. Rogers, and Maria Hadjifrangiskou. “Characterization of blue light irradiation effects on pathogenic and nonpathogenic Escherichia coli.Microbiologyopen 6, no. 4 (August 2017). https://doi.org/10.1002/mbo3.466.
Abana CM, Brannon JR, Ebbott RA, Dunigan TL, Guckes KR, Fuseini H, et al. Characterization of blue light irradiation effects on pathogenic and nonpathogenic Escherichia coli. Microbiologyopen. 2017 Aug;6(4).
Abana, Courtney M., et al. “Characterization of blue light irradiation effects on pathogenic and nonpathogenic Escherichia coli.Microbiologyopen, vol. 6, no. 4, Aug. 2017. Pubmed, doi:10.1002/mbo3.466.
Abana CM, Brannon JR, Ebbott RA, Dunigan TL, Guckes KR, Fuseini H, Powers J, Rogers BR, Hadjifrangiskou M. Characterization of blue light irradiation effects on pathogenic and nonpathogenic Escherichia coli. Microbiologyopen. 2017 Aug;6(4).
Journal cover image

Published In

Microbiologyopen

DOI

EISSN

2045-8827

Publication Date

August 2017

Volume

6

Issue

4

Location

England

Related Subject Headings

  • Microbial Viability
  • Light
  • Escherichia coli
  • Colony Count, Microbial
  • Adenosine Triphosphate
  • 3107 Microbiology
  • 3101 Biochemistry and cell biology
  • 0605 Microbiology