Optical tweezers: Probing biological surfaces


Journal Article

A pair of optical tweezers is an eminent tool for manipulating biological specimens at the macromolecular level. Optical tweezers measure corresponding forces and distances typically in the pico Newton and nanometer regim0es. Compared to the Atomic Force Microscope (AFM) optical tweezers are capable of accurately measuring forces which are orders of magnitude lower than those obtainable with AFM. We have built an experimental setup based on optical tweezers and in this paper describe its technical properties, design, abilities, and use in probing biological surfaces.

Duke Authors

Cited Authors

  • Oddershede, L; Grego, S; Nørrelykke, SF; Berg-Sørensen, K

Published Date

  • December 1, 2001

Published In

Volume / Issue

  • 2 / 2

Start / End Page

  • 129 - 137

International Standard Serial Number (ISSN)

  • 1355-185X

Citation Source

  • Scopus