Clinical guidelines for the management of acute viral infections in patients with systemic lupus erythematosus.


Journal Article (Review)

In recent decades, many research groups have focused on the role of viral infections in the etiopathogenesis of systemic lupus erythematosus (SLE), the so-called "viral hypothesis". The main candidates are herpes viruses such as Epstein-Barr virus (EBV) and cytomegalovirus (CMV), which have a high seroprevalence in the general population. However, a viral causal agent of SLE has not yet been discovered, although many interesting clinical findings on the complex interactions between viruses and SLE have been made. This review analyzes 88 cases of acute viral infections in adult patients with SLE and identifies situations in which viral infections influenced the diagnosis, prognosis or treatment of SLE. We also propose clinical guidelines for the management of these infections in patients with SLE.

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Cited Authors

  • Ramos-Casals, M; Cuadrado, MJ; Alba, P; Sanna, G; Brito-Zerón, P; Bertolaccini, L; Babini, A; Moreno, A; D'Cruz, D; Khamashta, MA

Published Date

  • December 2009

Published In

Volume / Issue

  • 100 / 6

Start / End Page

  • 437 - 446

PubMed ID

  • 20010479

Pubmed Central ID

  • 20010479

Electronic International Standard Serial Number (EISSN)

  • 1827-1669

International Standard Serial Number (ISSN)

  • 0026-4806


  • eng