Community-acquired methicillin-resistant Staphylococcus aureus meningitis complicated by cerebral infarction. Role of antibiotic combination of linezolid plus levofloxacin.

Published

Journal Article

The therapeutic options available for central nervous system (CNS) infections due to resistant Gram-positive cocci remain limited. We report an unusual case of community-acquired methicillin-resistant Staphylococcus aureus meningitis complicated by cerebral infarction in the middle cerebral artery territory in a previously healthy young male. After an initial vancomycin-based regimen, treatment was completed with a seven-week course of linezolid and levofloxacin. The potential role of such a combination and, particularly, linezolid as a first-line therapy in serious CNS infections is also discussed.

Full Text

Cited Authors

  • Fernández-Ruiz, M; Cervera, C; Pitart, C; Pérez, G; del Río, A; Miró, JM; Marco, F; Moreno, A

Published Date

  • January 2010

Published In

Volume / Issue

  • 49 / 18

Start / End Page

  • 1971 - 1974

PubMed ID

  • 20847500

Pubmed Central ID

  • 20847500

Electronic International Standard Serial Number (EISSN)

  • 1349-7235

International Standard Serial Number (ISSN)

  • 0918-2918

Digital Object Identifier (DOI)

  • 10.2169/internalmedicine.49.3942

Language

  • eng