Kidney transplantation and waiting list for renal transplantation for human immunodeficiency virus patients.

Published

Journal Article

INTRODUCTION: The aim of this study was to evaluate the experience of a renal transplantation unit in the management of human immunodeficiency virus (HIV)-infected patients with end-stage renal disease (ESRD). METHODS: A prospective study was performed between 2005 and 2010 among 23 patients with ESRD. RESULTS: In this study 83% of HIV-infected patients with ESRD were included on the waiting list for renal transplantation with 4 patients in a clinical evaluation phase. During the follow-up, 52% of waiting list patients (n = 11) received a renal transplant, and 1 patient underwent a simultaneous kidney-pancreas transplantation. Among the waiting list group we observed a significant later exclusion (43%; n = 3). Among the transplanted group there was a high but clinically inconsequential prevalence of acute tubular necrosis (36%; n = 4) and acute rejection episodes (36%; n = 4). The renal function showed a serum creatinine of 1.1 mg/dL at a follow-up of 24 + 12 months. All patients on the waiting list and after the transplantation are prescribed combined antiretroviral treatment (cART) with a low viral load <50 with CD4 >200. CONCLUSIONS: HIV-infected patients with ESRD should be considered to be candidates for renal transplantation if they meet the HIV inclusion criteria. Renal transplantation in adequately selected HIV-infected patients is a safe procedure with acceptable patient and graft survivals.

Full Text

Cited Authors

  • Martina, MN; Cofan, F; Suarez, A; Masso, E; Trullas, JC; Cervera, C; Moreno, A; Oppenheimer, F; Miiro, JM; Campistol, JM

Published Date

  • July 2011

Published In

Volume / Issue

  • 43 / 6

Start / End Page

  • 2179 - 2181

PubMed ID

  • 21839227

Pubmed Central ID

  • 21839227

Electronic International Standard Serial Number (EISSN)

  • 1873-2623

International Standard Serial Number (ISSN)

  • 0041-1345

Digital Object Identifier (DOI)

  • 10.1016/j.transproceed.2011.05.024

Language

  • eng