Building evidence and measuring clinical outcomes for genomic medicine.
Publication
, Journal Article
Peterson, JF; Roden, DM; Orlando, LA; Ramirez, AH; Mensah, GA; Williams, MS
Published in: Lancet
August 17, 2019
Human genomic sequencing has potential diagnostic, prognostic, and therapeutic value across a wide breadth of clinical disciplines. One barrier to widespread adoption is the paucity of evidence for improved outcomes in patients who do not already have an indication for more focused testing. In this Series paper, we review clinical outcome studies in genomic medicine and discuss the important features and key challenges to building evidence for next generation sequencing in the context of routine patient care.
Duke Scholars
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Published In
Lancet
DOI
EISSN
1474-547X
Publication Date
August 17, 2019
Volume
394
Issue
10198
Start / End Page
604 / 610
Location
England
Related Subject Headings
- Standard of Care
- Precision Medicine
- Patient Outcome Assessment
- Humans
- High-Throughput Nucleotide Sequencing
- Genomics
- Genome, Human
- General & Internal Medicine
- Diagnostic Tests, Routine
- 42 Health sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Peterson, J. F., Roden, D. M., Orlando, L. A., Ramirez, A. H., Mensah, G. A., & Williams, M. S. (2019). Building evidence and measuring clinical outcomes for genomic medicine. Lancet, 394(10198), 604–610. https://doi.org/10.1016/S0140-6736(19)31278-4
Peterson, Josh F., Dan M. Roden, Lori A. Orlando, Andrea H. Ramirez, George A. Mensah, and Marc S. Williams. “Building evidence and measuring clinical outcomes for genomic medicine.” Lancet 394, no. 10198 (August 17, 2019): 604–10. https://doi.org/10.1016/S0140-6736(19)31278-4.
Peterson JF, Roden DM, Orlando LA, Ramirez AH, Mensah GA, Williams MS. Building evidence and measuring clinical outcomes for genomic medicine. Lancet. 2019 Aug 17;394(10198):604–10.
Peterson, Josh F., et al. “Building evidence and measuring clinical outcomes for genomic medicine.” Lancet, vol. 394, no. 10198, Aug. 2019, pp. 604–10. Pubmed, doi:10.1016/S0140-6736(19)31278-4.
Peterson JF, Roden DM, Orlando LA, Ramirez AH, Mensah GA, Williams MS. Building evidence and measuring clinical outcomes for genomic medicine. Lancet. 2019 Aug 17;394(10198):604–610.
Published In
Lancet
DOI
EISSN
1474-547X
Publication Date
August 17, 2019
Volume
394
Issue
10198
Start / End Page
604 / 610
Location
England
Related Subject Headings
- Standard of Care
- Precision Medicine
- Patient Outcome Assessment
- Humans
- High-Throughput Nucleotide Sequencing
- Genomics
- Genome, Human
- General & Internal Medicine
- Diagnostic Tests, Routine
- 42 Health sciences