Hepatocellular adenomas: Understanding the pathomolecular lexicon, MRI features, terminology, and pitfalls to inform a standardized approach.

Journal Article (Journal Article;Review)

Hepatocellular adenomas (HCAs) are benign hepatic tumors that can be complicated by bleeding and/or malignant transformation. The epidemiology of HCAs has changed over recent decades, primarily influenced by an increased incidence of obesity in both men and women. Currently, at least eight distinct pathomolecular subtypes of HCAs have been identified, several of which have distinguishing and pertinent imaging features on MRI. Emerging evidence suggests that hepatobiliary phase appearance may provide diagnostic and prognostic information. The purpose of this article is to review the current pathomolecular lexicon and imaging features with emphasis on hepatobiliary phase appearance. Level of Evidence: 5 Technical Efficacy: Stage 3 J. Magn. Reson. Imaging 2020;51:1630-1640.

Full Text

Duke Authors

Cited Authors

  • Zulfiqar, M; Sirlin, CB; Yoneda, N; Ronot, M; Hecht, EM; Chernyak, V; Matsui, O; Bastati, N; Ba-Ssalamah, A; Chatterjee, D; Bashir, M; Fowler, KJ

Published Date

  • June 2020

Published In

Volume / Issue

  • 51 / 6

Start / End Page

  • 1630 - 1640

PubMed ID

  • 31418986

Electronic International Standard Serial Number (EISSN)

  • 1522-2586

Digital Object Identifier (DOI)

  • 10.1002/jmri.26902


  • eng

Conference Location

  • United States