Sudden Unexpected Death in a Child From an Anaplastic Ependymoma.

Journal Article (Journal Article)

Primary central nervous system tumors are an extremely rare cause of sudden, unexpected death in children as most patients develop symptoms because of increased intracranial pressure and seek medical attention. Rarely, a forensic pathologist may encounter a primary intracranial neoplasm in a pediatric decedent that was not suspected before death. Herein, we present a case of a supratentorial neuroepithelial tumor found at autopsy in a 3-year-old African American boy without any reported significant medical history. The tumor had significant mass effect and caused cerebral edema, which ultimately resulted in transtentorial herniation and death. The gross, histopathological, immunohistochemical, and ultrastructural findings were most consistent with an anaplastic ependymoma.

Full Text

Duke Authors

Cited Authors

  • Harrison, WT; Bouldin, T; Buckley, A; Estrada, J; McLendon, R; Janssen, K

Published Date

  • September 2019

Published In

Volume / Issue

  • 40 / 3

Start / End Page

  • 275 - 278

PubMed ID

  • 30958386

Electronic International Standard Serial Number (EISSN)

  • 1533-404X

Digital Object Identifier (DOI)

  • 10.1097/PAF.0000000000000480


  • eng

Conference Location

  • United States