Long-term use of temozolomide: could you use temozolomide safely for life in gliomas?
Published
Journal Article
Temozolomide (TMZ) is an alkylating agent used in the management of gliomas. Although TMZ is generally safe and acute toxicity is well documented, there are limited data on long-term toxicities. We present three patients with glioma; all patients started on TMZ after having progressed following primary treatment. These patients have continued TMZ for 5 years, 7 years and 8 years respectively. So far they have had no serious side effects. We discuss these patients while raising the question of prolonged TMZ use.
Full Text
Duke Authors
Cited Authors
- Khasraw, M; Bell, D; Wheeler, H
Published Date
- June 2009
Published In
Volume / Issue
- 16 / 6
Start / End Page
- 854 - 855
PubMed ID
- 19303779
Pubmed Central ID
- 19303779
International Standard Serial Number (ISSN)
- 0967-5868
Digital Object Identifier (DOI)
- 10.1016/j.jocn.2008.09.005
Language
- eng
Conference Location
- Scotland