Angiotensin converting enzyme in renal ontogeny: hypothesis for multiple roles.
Journal Article
Angiotensin converting enzyme (ACE) has multiple effects both as the enzyme which cleaves angiotensin II from angiotensin I and as that which breaks down bradykinin. The present study examines ACE mRNA and protein expression in the rat kidney during development. Changes in distribution and expression during development are consistent with suggestions that the renin angiotensin system is important in growth modulation, vascular development and regulation, and protein reabsorption.
Full Text
Duke Authors
Cited Authors
- Jung, FF; Bouyounes, B; Barrio, R; Tang, SS; Diamant, D; Ingelfinger, JR
Published Date
- December 1993
Published In
Volume / Issue
- 7 / 6
Start / End Page
- 834 - 840
PubMed ID
- 8130118
Pubmed Central ID
- 8130118
International Standard Serial Number (ISSN)
- 0931-041X
Digital Object Identifier (DOI)
- 10.1007/BF01213370
Language
- eng
Conference Location
- Germany