Angiotensin converting enzyme in renal ontogeny: hypothesis for multiple roles.

Journal Article

Angiotensin converting enzyme (ACE) has multiple effects both as the enzyme which cleaves angiotensin II from angiotensin I and as that which breaks down bradykinin. The present study examines ACE mRNA and protein expression in the rat kidney during development. Changes in distribution and expression during development are consistent with suggestions that the renin angiotensin system is important in growth modulation, vascular development and regulation, and protein reabsorption.

Full Text

Duke Authors

Cited Authors

  • Jung, FF; Bouyounes, B; Barrio, R; Tang, SS; Diamant, D; Ingelfinger, JR

Published Date

  • December 1993

Published In

Volume / Issue

  • 7 / 6

Start / End Page

  • 834 - 840

PubMed ID

  • 8130118

Pubmed Central ID

  • 8130118

International Standard Serial Number (ISSN)

  • 0931-041X

Digital Object Identifier (DOI)

  • 10.1007/BF01213370


  • eng

Conference Location

  • Germany