Ring-Opening Copolymerization of Maleic Anhydride with Functional Epoxides: Poly(propylene fumarate) Analogues Capable of Post-Polymerization Modification.

Journal Article (Journal Article)

Three functional epoxides were copolymerized with maleic anhydride to yield degradable poly(propylene fumarate) analogues. The polymers were modified post-polymerization and post-printing with either click-type addition reactions or UV deprotection to either attach bioactive species or increase the hydrophilicity. Successful dye attachment, induced wettability, and improved cell spreading show the viability of these analogues in biomaterials applications.

Full Text

Duke Authors

Cited Authors

  • Chen, Y; Wilson, JA; Petersen, SR; Luong, D; Sallam, S; Mao, J; Wesdemiotis, C; Becker, ML

Published Date

  • September 2018

Published In

Volume / Issue

  • 57 / 39

Start / End Page

  • 12759 - 12764

PubMed ID

  • 30080946

Electronic International Standard Serial Number (EISSN)

  • 1521-3773

International Standard Serial Number (ISSN)

  • 1433-7851

Digital Object Identifier (DOI)

  • 10.1002/anie.201807419


  • eng