Strain-promoted cross-linking of PEG-based hydrogels via copper- free cycloaddition

Journal Article (Journal Article)

The synthesis of a 4-dibenzocyclooctynol (DIBO) functionalized poly(ethylene glycol) (PEG) and fabrication of hydrogels via strain-promoted, metal-free, azide-alkyne cycloaddition is reported. The resulting hydrogel materials provide a versatile alternative to encapsulate cells that are sensitive to photochemical or chemical cross-linking mechanisms. © 2012 American Chemical Society.

Full Text

Duke Authors

Cited Authors

  • Zheng, J; Smith Callahan, LA; Hao, J; Guo, K; Wesdemiotis, C; Weiss, RA; Becker, ML

Published Date

  • August 21, 2012

Published In

Volume / Issue

  • 1 / 8

Start / End Page

  • 1071 - 1073

Electronic International Standard Serial Number (EISSN)

  • 2161-1653

Digital Object Identifier (DOI)

  • 10.1021/mz3003775

Citation Source

  • Scopus