Single-Session CT-Guided Percutaneous Microwave Ablation of Bilateral Adrenal Gland Hyperplasia Due to Ectopic ACTH Syndrome.

Journal Article (Journal Article)

Bilateral adrenalectomy is currently the only available treatment for adrenocorticotropic hormone (ACTH)-dependent Cushing's syndrome (ectopic ACTH syndrome) that is refractory to pharmacologic therapy. We describe two patients with refractory ectopic ACTH syndrome who were treated with CT-guided percutaneous microwave ablation of both hyperplastic adrenal glands in a single session: O ne was not a surgical candidate, and the other had undergone unsuccessful surgery. Following the procedure, both patients achieved substantial decreases in serum cortisol, symptomatic improvement, and decreased anti-hypertensive medication requirements.

Full Text

Duke Authors

Cited Authors

  • Sarma, A; Shyn, PB; Vivian, MA; Ng, J-M; Tuncali, K; Lorch, JH; Zaheer, SN; Gordon, MS; Silverman, SG

Published Date

  • October 2015

Published In

Volume / Issue

  • 38 / 5

Start / End Page

  • 1335 - 1338

PubMed ID

  • 25762486

Electronic International Standard Serial Number (EISSN)

  • 1432-086X

Digital Object Identifier (DOI)

  • 10.1007/s00270-015-1056-9


  • eng

Conference Location

  • United States