Damage Control in the Developing Brain: Tradeoffs and Consequences.

Journal Article (Journal Article)

Genomic surveillance is crucial for shaping brain development. However, are these mechanisms always beneficial, and can they be manipulated to ameliorate neurodevelopmental disease? A recent paper by Shi et al. (Nat. Commun., 2019) sheds light on these questions and examines the consequences of both inducing genomic instability and suppressing safeguard mechanisms for the development of the cerebral cortex.

Full Text

Duke Authors

Cited Authors

  • Alsina, FC; Silver, DL

Published Date

  • October 2019

Published In

Volume / Issue

  • 42 / 10

Start / End Page

  • 661 - 663

PubMed ID

  • 31447171

Electronic International Standard Serial Number (EISSN)

  • 1878-108X

Digital Object Identifier (DOI)

  • 10.1016/j.tins.2019.08.004


  • eng

Conference Location

  • England