Damage Control in the Developing Brain: Tradeoffs and Consequences.

Journal Article (Journal Article)

Genomic surveillance is crucial for shaping brain development. However, are these mechanisms always beneficial, and can they be manipulated to ameliorate neurodevelopmental disease? A recent paper by Shi et al. (Nat. Commun., 2019) sheds light on these questions and examines the consequences of both inducing genomic instability and suppressing safeguard mechanisms for the development of the cerebral cortex.

Full Text

Published version (via Digital Object Identifier)
Link to Item

Duke Authors

Alsina, Fernando
Silver, Debra Lynn

Cited Authors

Alsina, FC; Silver, DL

Published Date

October 2019

Published In

Trends Neurosci

Volume / Issue

42 / 10

Start / End Page

661 - 663

PubMed ID

31447171

Electronic International Standard Serial Number (EISSN)

1878-108X

Digital Object Identifier (DOI)

10.1016/j.tins.2019.08.004

Language

Conference Location

England

Scholars@Duke