Damage Control in the Developing Brain: Tradeoffs and Consequences.
Journal Article (Journal Article)
Genomic surveillance is crucial for shaping brain development. However, are these mechanisms always beneficial, and can they be manipulated to ameliorate neurodevelopmental disease? A recent paper by Shi et al. (Nat. Commun., 2019) sheds light on these questions and examines the consequences of both inducing genomic instability and suppressing safeguard mechanisms for the development of the cerebral cortex.
Full Text
Duke Authors
Cited Authors
- Alsina, FC; Silver, DL
Published Date
- October 2019
Published In
Volume / Issue
- 42 / 10
Start / End Page
- 661 - 663
PubMed ID
- 31447171
Electronic International Standard Serial Number (EISSN)
- 1878-108X
Digital Object Identifier (DOI)
- 10.1016/j.tins.2019.08.004
Language
- eng
Conference Location
- England