Radiologic Considerations and Standardization of Malignant Pleural Mesothelioma Imaging Within Clinical Trials: Consensus Statement from the NCI Thoracic Malignancy Steering Committee - International Association for the Study of Lung Cancer - Mesothelioma Applied Research Foundation Clinical Trials Planning Meeting.

Journal Article (Journal Article)

Detailed guidelines pertaining to radiological assessment of malignant pleural mesothelioma are currently lacking due to the rarity of the disease, complex morphology, propensity to invade multiple planes simultaneously, and lack of specific recommendations within the radiology community about assessment, reporting, and follow-up. In March 2017, a multidisciplinary meeting of mesothelioma experts was co-sponsored by the National Cancer Institute Thoracic Malignancy Steering Committee, International Association for the Study of Lung Cancer, and the Mesothelioma Applied Research Foundation. One of the outcomes of this conference was the foundation of detailed, multidisciplinary consensus imaging and management guidelines. Here, we present the recommendations for radiologic assessment of malignant pleural mesothelioma in the setting of clinical trial enrollment. We discuss optimization of imaging parameters across modalities, standardized reporting, and response assessment within clinical trials.

Full Text

Duke Authors

Cited Authors

  • Gill, RR; Tsao, AS; Kindler, HL; Richards, WG; Armato, SG; Francis, RJ; Gomez, DR; Dahlberg, S; Rimner, A; Simone, CB; de Perrot, M; Blumenthal, G; Adjei, AA; Bueno, R; Harpole, DH; Hesdorffer, M; Hirsch, FR; Pass, HI; Yorke, E; Rosenzweig, K; Burt, B; Fennell, DA; Lindwasser, W; Malik, S; Peikert, T; Mansfield, AS; Salgia, R; Yang, H; Rusch, VW; Nowak, AK

Published Date

  • October 2019

Published In

Volume / Issue

  • 14 / 10

Start / End Page

  • 1718 - 1731

PubMed ID

  • 31470129

Electronic International Standard Serial Number (EISSN)

  • 1556-1380

Digital Object Identifier (DOI)

  • 10.1016/j.jtho.2019.08.012


  • eng

Conference Location

  • United States