Spontaneous Intracranial Hypotension: Pathogenesis, Diagnosis, and Treatment.

Journal Article (Journal Article;Review)

Spontaneous intracranial hypotension (SIH) is a clinical syndrome that is increasingly recognized as an important and treatable secondary cause of headaches. Insight into the condition has evolved significantly over the past decade, resulting in a greater understanding of the underlying pathophysiology, development of new diagnostic imaging tools, and a broadening array of targeted treatment options. This article reviews the clinical presentation and pathogenesis of SIH, discusses the important role of imaging in diagnosis, and describes how imaging guides treatment.

Full Text

Duke Authors

Cited Authors

  • Kranz, PG; Gray, L; Malinzak, MD; Amrhein, TJ

Published Date

  • November 2019

Published In

Volume / Issue

  • 29 / 4

Start / End Page

  • 581 - 594

PubMed ID

  • 31677732

Electronic International Standard Serial Number (EISSN)

  • 1557-9867

Digital Object Identifier (DOI)

  • 10.1016/j.nic.2019.07.006


  • eng

Conference Location

  • United States