NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Colorectal, Version 2.2019.


Journal Article

Identifying individuals with hereditary syndromes allows for improved cancer surveillance, risk reduction, and optimized management. Establishing criteria for assessment allows for the identification of individuals who are carriers of pathogenic genetic variants. The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Colorectal provide recommendations for the assessment and management of patients with high-risk colorectal cancer syndromes. These NCCN Guidelines Insights focus on criteria for the evaluation of Lynch syndrome and considerations for use of multigene testing in the assessment of hereditary colorectal cancer syndromes.

Full Text

Duke Authors

Cited Authors

  • Gupta, S; Provenzale, D; Llor, X; Halverson, AL; Grady, W; Chung, DC; Haraldsdottir, S; Markowitz, AJ; Slavin, TP; Hampel, H; CGC, ; Ness, RM; Weiss, JM; Ahnen, DJ; Chen, L-M; Cooper, G; Early, DS; Giardiello, FM; Hall, MJ; Hamilton, SR; Kanth, P; Klapman, JB; Lazenby, AJ; Lynch, PM; Mayer, RJ; Mikkelson, J; CGC, ; Peter, S; Regenbogen, SE; Dwyer, MA; CGC, ; Ogba, N

Published Date

  • September 1, 2019

Published In

Volume / Issue

  • 17 / 9

Start / End Page

  • 1032 - 1041

PubMed ID

  • 31487681

Pubmed Central ID

  • 31487681

Electronic International Standard Serial Number (EISSN)

  • 1540-1413

Digital Object Identifier (DOI)

  • 10.6004/jnccn.2019.0044


  • eng

Conference Location

  • United States