Small Bowel Adenocarcinoma, Version 1.2020, NCCN Clinical Practice Guidelines in Oncology.

Journal Article (Journal Article)

Small bowel adenocarcinoma (SBA) is a rare malignancy of the gastrointestinal tract that has increased in incidence across recent years. Often diagnosed at an advanced stage, outcomes for SBA are worse on average than for other related malignancies, including colorectal cancer. Due to the rarity of this disease, few studies have been done to direct optimal treatment, although recent data have shown that SBA responds to treatment differently than colorectal cancer, necessitating a separate approach to treatment. The NCCN Guidelines for Small Bowel Adenocarcinoma were created to establish an evidence-based standard of care for patients with SBA. These guidelines provide recommendations on the workup of suspected SBA, primary treatment options, adjuvant treatment, surveillance, and systemic therapy for metastatic disease. Additionally, principles of imaging and endoscopy, pathologic review, surgery, radiation therapy, and survivorship are described.

Full Text

Duke Authors

Cited Authors

  • Benson, AB; Venook, AP; Al-Hawary, MM; Arain, MA; Chen, Y-J; Ciombor, KK; Cohen, SA; Cooper, HS; Deming, DA; Garrido-Laguna, I; Grem, JL; Hoffe, SE; Hubbard, J; Hunt, S; Kamel, A; Kirilcuk, N; Krishnamurthi, S; Messersmith, WA; Meyerhardt, J; Miller, ED; Mulcahy, MF; Nurkin, S; Overman, MJ; Parikh, A; Patel, H; Pedersen, KS; Saltz, LB; Schneider, C; Shibata, D; Skibber, JM; Sofocleous, CT; Stoffel, EM; Stotsky-Himelfarb, E; Willett, CG; Johnson-Chilla, A; Gregory, KM; Gurski, LA

Published Date

  • September 1, 2019

Published In

Volume / Issue

  • 17 / 9

Start / End Page

  • 1109 - 1133

PubMed ID

  • 31487687

Electronic International Standard Serial Number (EISSN)

  • 1540-1413

Digital Object Identifier (DOI)

  • 10.6004/jnccn.2019.0043


  • eng

Conference Location

  • United States