Impact of depression and anxiety on the quality of life of constipated patients.

Journal Article (Journal Article)

Constipation negatively affects quality of life (QOL), however, the specific mechanisms through which this relationship occurs are unclear. The present study examined anxiety and depression as potential mediators of the relationship between constipation severity and QOL in a sample of 142 constipated patients. Results indicated that depression symptom severity mediated the relationship between constipation severity and mental health-related QOL. For patients meeting diagnostic criteria for Major Depressive Disorder, indirect effects were observed in the relationship between constipation severity and both physical and mental health-related QOL. Anxiety did not contribute to this model. Treating depression may be useful in improving QOL in severely constipated patients, which highlights the importance of psychological screening and treatment referrals in primary care settings.

Full Text

Duke Authors

Cited Authors

  • Albiani, JJ; Hart, SL; Katz, L; Berian, J; Del Rosario, A; Lee, J; Varma, M

Published Date

  • March 2013

Published In

Volume / Issue

  • 20 / 1

Start / End Page

  • 123 - 132

PubMed ID

  • 22581107

Electronic International Standard Serial Number (EISSN)

  • 1573-3572

Digital Object Identifier (DOI)

  • 10.1007/s10880-012-9306-3


  • eng

Conference Location

  • United States