Skip to main content

Treatment of L5-S1 spondyloptosis with stand-alone anterior lumbar interbody fusion in a patient with neurofibromatosis.

Publication ,  Journal Article
Cheaney, B; Krause, KL; Jung, E; Than, KD
Published in: Br J Neurosurg
June 2023

BACKGROUND: Neurofibromatosis type 1 (NF1) is a multisystem disorder that causes multiple tumor formations throughout the nervous system. Common spinal dysplasias seen with NF1, such as dural ectasia (DE), often undergo modulation and predispose these patients to spondylolisthesis, making surgical treatment challenging. CASE DESCRIPTION: A patient with NF1 presented with a 12-year-history of back and left lower extremity radicular pain. Lumbar spine magnetic resonance imaging revealed developmental anomalies with severe DE and associated scalloping of the L4-S1 vertebral bodies and severe L5-S1 Meyerding grade 4 spondylolisthesis. During surgery, post-positioning x-rays demonstrated a grade 5 spondyloptosis. The patient underwent an L5-S1 stand-alone anterior lumbar interbody fusion (ALIF). The final construct was an ALIF cage with one screw into S1, without an anterior plate. By 3-months post-operative, there was complete resolution of preoperative symptoms and at 2 year follow-up the patient was asymptomatic with stable hardware and solid bony fusion. To the authors' knowledge, this is the first report of spondyloptosis treated with a stand-alone ALIF in a patient with NF1 and severe DE.

Duke Scholars

Published In

Br J Neurosurg

DOI

EISSN

1360-046X

Publication Date

June 2023

Volume

37

Issue

3

Start / End Page

512 / 517

Location

England

Related Subject Headings

  • Treatment Outcome
  • Spondylolisthesis
  • Spinal Fusion
  • Radiography
  • Neurology & Neurosurgery
  • Neurofibromatoses
  • Lumbosacral Region
  • Lumbar Vertebrae
  • Humans
  • 3209 Neurosciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Cheaney, B., Krause, K. L., Jung, E., & Than, K. D. (2023). Treatment of L5-S1 spondyloptosis with stand-alone anterior lumbar interbody fusion in a patient with neurofibromatosis. Br J Neurosurg, 37(3), 512–517. https://doi.org/10.1080/02688697.2019.1572868
Cheaney, Barry, Katie L. Krause, Enjae Jung, and Khoi D. Than. “Treatment of L5-S1 spondyloptosis with stand-alone anterior lumbar interbody fusion in a patient with neurofibromatosis.Br J Neurosurg 37, no. 3 (June 2023): 512–17. https://doi.org/10.1080/02688697.2019.1572868.
Cheaney, Barry, et al. “Treatment of L5-S1 spondyloptosis with stand-alone anterior lumbar interbody fusion in a patient with neurofibromatosis.Br J Neurosurg, vol. 37, no. 3, June 2023, pp. 512–17. Pubmed, doi:10.1080/02688697.2019.1572868.
Cheaney B, Krause KL, Jung E, Than KD. Treatment of L5-S1 spondyloptosis with stand-alone anterior lumbar interbody fusion in a patient with neurofibromatosis. Br J Neurosurg. 2023 Jun;37(3):512–517.

Published In

Br J Neurosurg

DOI

EISSN

1360-046X

Publication Date

June 2023

Volume

37

Issue

3

Start / End Page

512 / 517

Location

England

Related Subject Headings

  • Treatment Outcome
  • Spondylolisthesis
  • Spinal Fusion
  • Radiography
  • Neurology & Neurosurgery
  • Neurofibromatoses
  • Lumbosacral Region
  • Lumbar Vertebrae
  • Humans
  • 3209 Neurosciences