Clinical and radiographic outcomes after minimally invasive transforaminal lumbar interbody fusion.

Published online

Journal Article

OBJECTIVE: To evaluate outcomes after minimally invasive transforaminal lumbar interbody fusion (MI-TLIF). BACKGROUND: MI-TLIF is a relatively novel technique for treating symptomatic spondylolisthesis and degenerative disc disease of the lumbar spine. It has become a popular option for lumbar arthrodesis largely because of its potential to minimize iatrogenic trauma to the soft tissue, paraspinous muscles as well as to neural elements. METHODS: Literature search using PubMed database. RESULTS: Eight retrospective clinical studies and 1 prospective clinical study were identified. No randomized studies were found. The indications for surgery were low-back pain and/or radicular symptoms secondary to spondylolisthesis and/or degenerative disc disease. Analysis of radiographic outcomes demonstrated a fusion rate greater than 90% in the vast majority of patients. Patients also experienced a significant improvement in functional outcome parameters at a mean follow-up of 20 months. Comparison of functional outcomes of MI-TLIF patients to a similar matched cohort of patients who underwent conventional open TLIF did not demonstrate any statistically significant difference between both cohorts. CONCLUSION: For carefully selected patients, MI-TLIF has a very favorable long term outcome that is comparable to conventional open TLIF, with the added benefit of decreased adjacent tissue injury.

Full Text

Duke Authors

Cited Authors

  • Etame, AB; Wang, AC; Than, KD; Park, P

Published Date

  • 2010

Published In

Volume / Issue

  • 4 / 2

Start / End Page

  • 47 - 53

PubMed ID

  • 25802649

Pubmed Central ID

  • 25802649

International Standard Serial Number (ISSN)

  • 1935-9810

Digital Object Identifier (DOI)

  • 10.1016/j.esas.2010.03.002


  • eng

Conference Location

  • United States