DNA repair genes: contributions to prostate cancer predisposition and aggressiveness.

Journal Article (Journal Article)

Germline pathogenic mutations in DNA repair genes have been linked to prostate cancer risk and aggressiveness. This observation was facilitated by tumor sequencing of men with advanced prostate cancer and has important implications for clinical management. In addition, cascade testing will identify at-risk individuals who should be assessed for cancer risk.

Full Text

Duke Authors

Cited Authors

  • Boyle, J; Cooney, KA

Published Date

  • October 2019

Published In

Volume / Issue

  • 26 / 5 Suppl 2

Start / End Page

  • 10 - 11

PubMed ID

  • 31629416

International Standard Serial Number (ISSN)

  • 1195-9479


  • eng

Conference Location

  • Canada